Tropane Alkaloids: Chemistry, Pharmacology, Biosynthesis and Production
نویسندگان
چکیده
منابع مشابه
Tropane alkaloids from Latua pubiflora.
Four known tropane alkaloids were isolated from the leaves of the endemic Chilean plant Latua pubiflora (Solanaceae). For the first time; 3alpha-cinnamoyloxitropane and apoatropine are reported in this plant. Scopolamine and hyoscyamine were previously reported.
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The unique polycyclic fused ring systems of Daphniphyllum alkaloids, along with their extensive bioactivities, make this family of alkaloids especially attractive targets for total synthesis and biogenetic studies. Successive discoveries of new alkaloids with unprecedented skeletons have made a great contribution to structural diversities of alkaloids elaborated by plants of the genus Daphniphy...
متن کاملTropane alkaloids and toxicity of Convolvulus arvensis.
Horses in a few, localized northern Colorado pastures exhibited weight loss and colic. At post mortem, intestinal fibrosis and vascular sclerosis of the small intestine was identified. The pastures where the affected horses grazed were overrun by field bindweed (Convolvulus arvensis). Bindweed from the pasture was found to contain the tropane alkaloids tropine, pseudotropine, and tropinone and ...
متن کاملChirality and numbering of substituted tropane alkaloids.
The strict application of IUPAC rules for the numbering of tropane alkaloids is not always applied by authors and there is hence a lot of confusion in the literature. In most cases, the notation of 3, 6/7-disubstituted derivatives has been chosen arbitrarily, based on NMR and MS data, without taking into account the absolute configuration of these two carbons. This paper discusses the problem a...
متن کاملTropane alkaloids of Datura innoxia from Morocco.
Fifty three alkaloids were identified in the organs (roots, stems, leaves, flowers, and seeds) of Datura innoxia by GC/MS. Seventeen of them are reported for the first time for this species and one nor-derivative, 3-phenylacetoxynortropane (28), for the genus Datura. Furthermore, four new tropane esters were tentatively identified as 3-acetoxy-6,7-epoxytropane (acetylscopine) (10), 3-acetoxy-6-...
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ژورنال
عنوان ژورنال: Molecules
سال: 2019
ISSN: 1420-3049
DOI: 10.3390/molecules24040796